Rosacea
Aetiopathogenesis
- Multifactorial: Dysregulation of innate immunity + neurovascular dysfunction. Cathelicidin/LL-37 ↑ → Inflammation. Demodex folliculorum as a cofactor.
Clinical – Subtypes (according to Powell)
- I Erythematotelangiectatic Rosacea: Flush, persistent centrofacial erythema.
- II Papulopustular Rosacea: inflammatory papules/pustules, without comedones (DD Acne!).
- III Phymatous Rosacea: Rhinophyma most common. Sebaceous gland hyperplasia + fibrosis.
- IV Ocular Rosacea: Blepharitis + Conjunctivitis + Keratitis.
Special Forms
- Rosacea fulminans (Pyoderma faciale): Acute, young women, confluent abscesses + fistulas.
- Morbihan disease: Chronic solid facial edema.
- Granulomatous Rosacea: Firm, brownish papules (Diascopy positive).
Differential diagnoses
- Seborrhoeic dermatitis
- Lupus erythematosus gesicht
- Demodicosis
- Rosacea fulminans / Pyoderma faciale
- Airborne contact dermatitis
- Acne fulminans
- Acne vulgaris
- Dermatomyositis
Practise Rosacea in the app
Flashcards with spaced repetition, exam questions and spot-the-diagnosis on this topic – in DermaFuchs, free of charge.
In the DermaFuchs app: 15 flashcards · 4 clinical images
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More diseases of the skin appendages
- Acne fulminans
- Hidradenitis suppurativa (acne inversa)
- Acne vulgaris
- Alopecia areata
- Androgenetic alopecia
- Folliculitis (infectious)
- Lichen planopilaris
- Milia (milium)
Note: This page is intended for medical education and does not replace diagnosis or treatment decisions in individual cases. Treatment and follow-up content is available in the app.