ABCD² score after transient ischaemic attack

The ABCD² score estimates the risk of stroke in the first days after a transient ischaemic attack (TIA). It consists of five clinical items.

⚠︎ Learning tool for medical education – not for use in patients or for treatment decisions.

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C – Clinical features
D – Duration of symptoms
–points

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Classification (original publication)

ScoreClassification (original publication)
0–3Low risk – 2-day stroke risk about 1% in the Johnston 2007 validation
4–5Moderate risk – 2-day stroke risk about 4% in the Johnston 2007 validation
6–7High risk – 2-day stroke risk about 8% in the Johnston 2007 validation

Limitations

Even a low score does not rule out early stroke. In later studies, the ABCD² score discriminated less well between high- and low-risk patients than in the original study (Perry 2011: area under the curve 0.56–0.65; meta-analysis by Wardlaw 2015: a score of 4 or more is sensitive but not very specific); it does not replace imaging or vascular assessment.

FAQ

What does ABCD² stand for?▾

Age, blood pressure, clinical features, duration and diabetes – two Ds, hence the “²”.

References

  1. Johnston SC et al. Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack. Lancet 2007;369:283–92. · PubMed
  2. Perry JJ et al. Prospective validation of the ABCD2 score for patients in the emergency department with transient ischemic attack. CMAJ 2011;183:1137–45. · PubMed
  3. Wardlaw JM et al. ABCD2 score and secondary stroke prevention: meta-analysis and effect per 1,000 patients triaged. Neurology 2015;85:373–80. · PubMed

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Intended purpose: learning tool for medical education only. Not intended for use in patients or for diagnostic or treatment decisions; not a medical device. Calculations follow the cited original publications; no guarantee of completeness or correctness. Last updated: 10/2026 · Dr. Pascal Bafteh