eGFR calculator (CKD-EPI 2021)

The 2021 CKD-EPI equation estimates glomerular filtration rate from serum creatinine – without a race coefficient. The result is normalised to 1.73 m² body surface area.

⚠︎ Learning tool for medical education – not for use in patients or for treatment decisions.

Calculator

Unit
years
Sex
–ml/min/1.73 m²

🔒 Calculated only in your browser – nothing is stored or transmitted.

Classification (original publication)

ScoreClassification (original publication)
≥ 90G1 – normal or high – CKD only with markers of kidney damage, e.g. albuminuria
60–89G2 – mildly decreased – CKD only with markers of kidney damage
45–59G3a – mildly to moderately decreased
30–44G3b – moderately to severely decreased
15–29G4 – severely decreased
< 15G5 – kidney failure

Equation

eGFR = 142 × min(Scr/κ, 1)^α × max(Scr/κ, 1)^−1.200 × 0.9938^age × 1.012 [if female]. κ = 0.7 (female) or 0.9 (male), α = −0.241 (female) or −0.302 (male); Scr in mg/dl (µmol/l ÷ 88.4).

KDIGO classification

Chronic kidney disease is present if GFR is below 60 ml/min/1.73 m² for more than three months or markers of kidney damage (e.g. albuminuria) are present. The full KDIGO classification combines G category and albuminuria category (A1–A3).

Limitations

Creatinine-based eGFR is unreliable in unstable kidney function (acute kidney injury), extreme muscle mass, amputation, pregnancy and in children. A cystatin C-based estimate can complement it when uncertain.

FAQ

Why is there no race coefficient anymore?▾

The 2021 CKD-EPI equation was re-estimated without race because the coefficient lacks biological justification and led to misclassification.

Does the equation apply to children?▾

No, CKD-EPI is validated for adults aged 18 and over. Children require specific equations (e.g. Schwartz).

References

  1. Inker LA et al. New creatinine- and cystatin C-based equations to estimate GFR without race. N Engl J Med 2021;385:1737–49. · PubMed
  2. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int 2024;105(4S):S117–S314. · PubMed

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Intended purpose: learning tool for medical education only. Not intended for use in patients or for diagnostic or treatment decisions; not a medical device. Calculations follow the cited original publications; no guarantee of completeness or correctness. Last updated: 09/2026 · Dr. Pascal Bafteh